Arkhipova L T, Dolgova I G
Vestn Oftalmol. 2000 May-Jun;116(3):19-21.
Course of acute traumatic uveitis was evaluated in 146 patients with penetrating wounds of different severity in scores starting from the first days after the injury was inflicted and after operations performed in early terms after the injury. The inflammatory process normalized by weeks 2-3 in a favorable course, while in severe injuries and early reoperations and in wounds of the fourth degree of severity posttraumatic uveitis persisted during weeks 3-4, and 35.2% patients developed chronic posttraumatic uveitis. Clinical signs of immunological insufficiency, presenting mainly as the infectious syndrome (28%), were detected in 35.6% patients with penetrating injuries on the basis of case history analysis by means of a universal diagnostic chart and clinical findings. Penetrating wounds of the third and fourth degree of severity, reoperations during early terms after primary surgical treatment, chronic inflammatory diseases (mainly of the ENT and bronchopulmonary system, indicating secondary immunodeficiency, which necessitate prescription of immunocorrectors starting from the first days after the injury) are factors of risk of protracted or chronic course of posttraumatic uveitis.
对146例不同严重程度穿透伤患者的急性外伤性葡萄膜炎病程进行了评估，评分从受伤后的第一天以及受伤后早期进行手术后开始。在病情发展顺利的情况下，炎症过程在2至3周内恢复正常，而在严重损伤、早期再次手术以及严重程度为四级的伤口中，创伤后葡萄膜炎在3至4周内持续存在，35.2%的患者发展为慢性创伤后葡萄膜炎。通过通用诊断图表和临床检查结果对病例进行病史分析，在35.6%的穿透伤患者中检测到主要表现为感染综合征（28%）的免疫功能不全临床症状。严重程度为三级和四级的穿透伤、初次手术治疗后早期再次手术、慢性炎症性疾病（主要是耳鼻喉和支气管肺系统疾病，提示继发性免疫缺陷，受伤后第一天起就需要使用免疫调节剂）是创伤后葡萄膜炎病程迁延或慢性化的危险因素。
