Poliakova A N
Vopr Virusol. 1975 Jan-Feb(1):102-5.
A modification of acid precipitation of fibrin in immune ascitic fluids (IAF) employing beta-propiolactone has been developed. The procedure removes fibrin completely without affecting the titres of specific antibody. This modification is not inferior to previously described methods for fibrin removal from IAF and has a number of advantages. In addition to removing fibrin from IAF, beta-propiolactone prevents possible virus contamination of IAF and sterilizes the preparation additionally.
已开发出一种利用β-丙内酯对免疫腹水（IAF）中纤维蛋白的酸沉淀法进行的改良方法。该方法能完全去除纤维蛋白，且不影响特异性抗体的效价。这种改良方法在从IAF中去除纤维蛋白方面并不逊色于先前描述的方法，并且具有许多优点。除了从IAF中去除纤维蛋白外，β-丙内酯还可防止IAF可能受到病毒污染，并对制剂进行额外消毒。
