Zhao M, Liu Z, Su J
Second Clinical College of Nanjing University of Traditional Chinese Medicine and Pharmacy.
J Tradit Chin Med. 2000 Mar;20(1):26-9.
To study the time-effect relationship of action of acupuncture on the satiety center of ventromedial nucleus of hypothalamus (VMH) in rats with experimental obesity.
Microelectrode recording method of nerve cells and stereotaxic technique for brain were adopted with discharge frequency (Hz/s) of nerve impulse in VMH as the index, and the time-effect of acupuncture action in different periods between groups were observed.
Electric activity in acupuncture group was higher than in the obesity model group (P < 0.001) and the normal group (P < 0.01) respectively, and the curve of acupuncture action within 2 hours showed irregular fluctuation.
Acupuncture can increase excitability of the satiety center, with a better long-term effect.
研究针刺对实验性肥胖大鼠下丘脑腹内侧核（VMH）饱食中枢作用的时效关系。
采用神经细胞微电极记录方法及脑立体定位技术，以VMH神经冲动放电频率（Hz/s）为指标，观察不同时段针刺作用的时效关系。
针刺组电活动分别高于肥胖模型组（P<0.001）和正常组（P<0.01），2小时内针刺作用曲线呈不规则波动。
针刺可提高饱食中枢兴奋性，且远期效果较好。
