Abdi Hamid, Zhao Baixiao, Darbandi Mahsa, Ghayour-Mobarhan Majid, Tavallaie Shima, Rahsepar Amir Ali, Parizadeh Seyyed Mohammad Reza, Safariyan Mohammad, Nemati Mohsen, Mohammadi Maryam, Abbasi-Parizad Parisa, Darbandi Sara, Akhlaghi Saeed, Ferns Gordon A A
Departments of Acupuncture Therapy, Beijing University of Chinese Medicine, Beijing 100029, China.
ScientificWorldJournal. 2012;2012:603539. doi: 10.1100/2012/603539. Epub 2012 Apr 29.
A randomized controlled clinical trial in 196 obese subjects was performed to examine the effectiveness of body acupuncture on body weight loss, lipid profile and immunogenic and inflammatory markers. Subjects received authentic (cases) or sham (controls) acupuncture for 6 weeks in combination with a low-calorie diet. In the following 6 weeks, they received the low-calorie diet alone. Subjects were assessed at the beginning, 6 and 12 weeks later. Heat shock protein (Hsps)-27, 60, 65, 70 antibody titers and high sensitivity C-reactive protein (hs-CRP) levels were also assessed. A significant reduction in measures of adiposity and improvement in lipid profile were observed in both groups, but the levels of anti-Hsp-antibodies decreased in cases only. A reduction in anthropometric and lipid profile in cases were sustained in the second period, however, only changes in lipid profile were observed in the control group. Anti-Hsp-antibodies and hs-CRP levels continued to be reduced in cases but in controls only the reduction in hs-CRP remained. Changes in anthropometric parameters, lipid profile, and anti-Hsp-antibodies were more evident in cases. Body acupuncture in combination with diet restriction was effective in enhancing weight loss and improving dyslipidemia.
在196名肥胖受试者中进行了一项随机对照临床试验，以检验体针疗法对体重减轻、血脂谱以及免疫原性和炎症标志物的有效性。受试者接受真针刺（病例组）或假针刺（对照组）治疗6周，并结合低热量饮食。在接下来的6周里，他们仅接受低热量饮食。在开始时、6周后和12周后对受试者进行评估。还评估了热休克蛋白（Hsps）-27、60、65、70抗体滴度和高敏C反应蛋白（hs-CRP）水平。两组的肥胖指标均显著降低，血脂谱有所改善，但仅病例组的抗Hsp抗体水平下降。病例组在第二阶段维持了人体测量和血脂谱的降低，然而，对照组仅观察到血脂谱的变化。病例组的抗Hsp抗体和hs-CRP水平持续降低，但对照组仅hs-CRP有所降低。病例组的人体测量参数、血脂谱和抗Hsp抗体的变化更为明显。体针疗法结合饮食限制在促进体重减轻和改善血脂异常方面是有效的。
