[糖皮质激素与胰高血糖素在胎鼠肝脏精氨酸琥珀酸酶活性调控中的相互作用]
[Interaction of glucocorticosteroids with glucagon in the control of argininosuccinase activity in the fetal rat liver].
作者信息
Husson A, Vaillant R
出版信息
C R Seances Acad Sci D. 1979 Jan 29;288(4):421-3.
PMID:109224
Abstract
Exogenous glucagon, but not glucocorticosteroids cause a rise in argininosuccinase activity in the liver of 21.5 day old fetuses. When fetuses are deprived of glucocorticosteroids, glucagon is unable to promote the enzymic activity. This study indicates that glucocorticosteroids are required for the induction of the argininosuccinase activity by glucagon.
摘要
外源性胰高血糖素，而非糖皮质激素，会使21.5日龄胎儿肝脏中的精氨酸琥珀酸酶活性升高。当胎儿缺乏糖皮质激素时，胰高血糖素无法促进酶活性。这项研究表明，糖皮质激素是胰高血糖素诱导精氨酸琥珀酸酶活性所必需的。
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