Loeffler K U, Seifert P, Spitznas M
Alfried-Krupp-Labor Department of Ophthalmology, University of Bonn, Germany.
Hum Pathol. 2000 Jul;31(7):882-7. doi: 10.1053/hupa.2000.9549.
We report the clinical and histological findings in a tumor of the pigmented ciliary epithelium. The tumor was detected because it had caused a unilateral cataract, and it was removed by local resection because a malignant melanoma could not be excluded. The diagnosis was established by light microscopy, and additional immunohistochemical and detailed ultrastructural studies were performed. The so-called foam cells which are considered typical of these adenomas appear to be mostly light microscopic artifacts and had no ultrastructural equivalent in the sections examined from our tumor. Our results also strongly support the hypothesis that no true glandular elements are formed and that, apart from the neoplastic tissue architecture, most of the pathological findings are related to melanosomes.
我们报告了一例色素性睫状体上皮肿瘤的临床和组织学发现。该肿瘤因导致单侧白内障而被发现，由于不能排除恶性黑色素瘤，故通过局部切除将其切除。通过光学显微镜确诊，并进行了额外的免疫组织化学和详细的超微结构研究。这些腺瘤典型的所谓泡沫细胞似乎大多是光学显微镜下的假象，在我们肿瘤的切片中没有超微结构上的对应物。我们的结果也有力地支持了这样一种假说，即没有形成真正的腺性成分，并且除了肿瘤组织结构外，大多数病理发现都与黑素小体有关。
