光化性角化病是鳞状细胞癌。
Actinic keratosis is squamous cell carcinoma.
作者信息
Lober B A, Lober C W
机构信息
Division of Dermatology and Cutaneous Surgery, University of South Florida, Tampa, USA.
出版信息
South Med J. 2000 Jul;93(7):650-5.
BACKGROUND
The prevalence of nonmelanoma skin cancer in the United States is alarming. It can be most appropriately treated if the earliest manifestation of cutaneous squamous cell carcinoma is recognized.
METHODS
Clinical, histologic, and molecular biology, considerations were reviewed to determine whether actinic keratosis is the earliest clinical manifestation of cutaneous squamous cell carcinoma.
RESULTS
The clinical, histologic, and molecular parameters of actinic keratosis are those of squamous cell carcinoma.
CONCLUSION
Actinic keratosis does not transform, convert, or progress into cutaneous squamous cell carcinoma but is the earliest clinically recognizable manifestation of this malignancy.
背景
美国非黑色素瘤皮肤癌的患病率令人担忧。如果能识别出皮肤鳞状细胞癌的最早表现，就能得到最恰当的治疗。
方法
对临床、组织学和分子生物学方面的考虑因素进行了综述，以确定光化性角化病是否为皮肤鳞状细胞癌的最早临床表现。
结果
光化性角化病的临床、组织学和分子参数与鳞状细胞癌相同。
结论
光化性角化病不会转变、转化或进展为皮肤鳞状细胞癌，而是这种恶性肿瘤最早的临床可识别表现。
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