伴有横纹肌样转化的恶性脑膜瘤。

Malignant meningioma with rhabdoid transformation.

作者信息

Lee W H, Chen A, Chao D G, Harn H J, Lin S Z

机构信息

Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, National Defense University, Taipei, Taiwan, ROC.

出版信息

Zhonghua Yi Xue Za Zhi (Taipei). 2000 Jun;63(6):492-7.

PMID:10925541

Abstract

We report a rare case of recurrent meningioma with malignant change and rhabdoid transformation in a 54-year-old woman who presented with severe headache and progressive weakness of the right extremities. The patient had a history of atypical meningioma and had undergone a craniotomy to remove a tumor nine years earlier. We discuss the distinctive morphologic, immunohistochemical staining and ultrastructural features of a recurrent malignant meningioma. A meningioma with rhabdoid transformation may indicate aggressive biologic and clinical behavior of the tumor.

摘要

我们报告了一例罕见的复发性脑膜瘤伴恶性变及横纹肌样转化病例，患者为一名54岁女性，表现为严重头痛和右上肢进行性无力。该患者有非典型脑膜瘤病史，9年前曾接受开颅手术切除肿瘤。我们讨论了复发性恶性脑膜瘤独特的形态学、免疫组化染色及超微结构特征。伴有横纹肌样转化的脑膜瘤可能提示肿瘤具有侵袭性生物学行为和临床行为。