Zhirova S N, Gervazieva V B
Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2000 May-Jun(3):66-9.
The optimum method for obtaining allergenic preparation with high specific activity and stable physico-chemical characteristics from cockroaches of the species B. germanica was developed. The quantitative content of cockroach allergens Bla g1 and Bla g2 was determined in experimental batches. The age structure of sensitization to cockroaches in 124 bronchial asthma patients (50 adults and 74 children) was studied. Specific IgE antibodies to B. germanica were detected in 34% of the examined adults and 63.5% of the children.
已开发出从德国小蠊蟑螂中获取具有高比活性和稳定理化特性的变应原制剂的最佳方法。测定了实验批次中蟑螂变应原Bla g1和Bla g2的定量含量。研究了124例支气管哮喘患者（50名成人和74名儿童）对蟑螂致敏的年龄结构。在34%的受检成人和63.5%的儿童中检测到针对德国小蠊的特异性IgE抗体。
