硫酸吗啡对犬刺激胃液分泌的作用。
Action of morphine sulfphate on stimulated gastric secretion in dogs.
作者信息
Magee D F
出版信息
Gastroenterology. 1975 May;68(5 Pt 1):1340-3.
PMID:1092592
Abstract
In dogs morphine sulphate suppresses both 2-deoxy-D-glucose and pentagastrin-stimulated acid and pepsin secretion, but not histimaine- and pilocarpine-stimulated acid. This is consistent with the view that morphine both depresses acetylcholine release from cholinergic endings in the stomach and that pentagastrin acts by liberation of acetylcholine from these endings.
摘要
在犬类中，硫酸吗啡可抑制2-脱氧-D-葡萄糖和五肽胃泌素刺激引起的胃酸和胃蛋白酶分泌，但不抑制组胺和毛果芸香碱刺激引起的胃酸分泌。这与以下观点一致，即吗啡既抑制胃中胆碱能末梢释放乙酰胆碱，又认为五肽胃泌素通过从这些末梢释放乙酰胆碱而起作用。
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