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假饲对胃泌素刺激的犬胃酸分泌的抑制作用。

Inhibition of gastrin-stimulated canine acid secretion by sham-feeding.

作者信息

Sjödin L

出版信息

Scand J Gastroenterol. 1975;10(1):73-80.

PMID:1124342
Abstract

In dogs with a Heidenhain pouch and oesophageal and gastric fistulae, sham feeding inhibited pentagastrin-stimulated Heidenhain pouch acid output. When secretion was stimulated with a combination of pentagastrin and betanechol chloride, the inhibitory effect of sham feeding was less pronounced. Histamine-stimulated secretion was not inhibited by sham feeding. The inhibitory effect was not affected by extragastric abdominal vagotomy but was reduced or abolished by truncal vagotomy. The results are consistent with the hypothesis that vagal activity releases a hormone which has an inhibitory action on gastric acid secretion.

摘要

在具有海登海因小胃以及食管和胃瘘管的犬中,假饲抑制了五肽胃泌素刺激的海登海因小胃酸分泌。当用五肽胃泌素和氯化氨甲酰甲胆碱联合刺激分泌时,假饲的抑制作用不那么明显。组胺刺激的分泌不受假饲抑制。这种抑制作用不受胃外腹部迷走神经切断术的影响,但在迷走神经干切断术后减弱或消失。这些结果与迷走神经活动释放一种对胃酸分泌具有抑制作用的激素这一假说一致。

相似文献

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Inhibition of gastrin-stimulated canine acid secretion by sham-feeding.假饲对胃泌素刺激的犬胃酸分泌的抑制作用。
Scand J Gastroenterol. 1975;10(1):73-80.
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Effect of truncal vagotomy on gastrin release and Heidenhain pouch acid secretion in response to feeding in dogs.迷走神经干切断术对犬进食后胃泌素释放及海登海因小胃胃酸分泌的影响。
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Calcitonin gene related peptide inhibits basal, pentagastrin, histamine, and bethanecol stimulated gastric acid secretion.降钙素基因相关肽可抑制基础状态下、由五肽胃泌素、组胺和氨甲酰甲胆碱刺激引起的胃酸分泌。
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