Grieve R, Porsdal V, Hutton J, Wolfe C
Guy's, King's, and St. Thomas' School of Medicine.
Int J Technol Assess Health Care. 2000 Spring;16(2):684-95. doi: 10.1017/s0266462300101242.
This study compared the relative cost-effectiveness of stroke care provided in London and Copenhagen.
Hospitalized stroke patients at centers in London (1995-96) and Copenhagen (1994-95) were included. Each patient's use of hospital and community health services was recorded for 1 year after stroke. Center-specific unit costs were collected and converted into dollars using the Purchasing Power Parity Index. An incremental cost-effectiveness ratio (ICER) was calculated comparing a Copenhagen model of stroke care to a London model, using regression analysis to adjust for case-mix differences.
A total of 625 patients (297 in Copenhagen, 328 in London) were included in the analysis. Most patients in London (85%) were admitted to general medical wards, with 26% subsequently transferred to a stroke unit. In Copenhagen, 57% of patients were directly admitted to a stroke or neurology unit, with 23% then transferred to a separate rehabilitation hospital. The average length of total hospital stay was 11 days longer in Copenhagen. Patients in Copenhagen were less likely to die than those in London; for patients with cerebral infarction the hazard ratio after case-mix adjustment was 0.53 (95% CI from 0.35 to 0.80). However, a lower proportion of patients with hemorrhagic stroke died in London. The ICER of using the Copenhagen compared with the London model of care ranged from $21,579 to $37,444 per life-year gained for patients with cerebral infarctions.
The ICERs of the Copenhagen compared with the London model of care were within a range generally regarded as cost-effective.
本研究比较了伦敦和哥本哈根提供的中风护理的相对成本效益。
纳入伦敦(1995 - 96年)和哥本哈根(1994 - 95年)各中心的住院中风患者。记录每位患者中风后1年的医院和社区卫生服务使用情况。收集各中心的单位成本,并使用购买力平价指数换算成美元。计算将哥本哈根中风护理模式与伦敦模式进行比较的增量成本效益比(ICER),使用回归分析调整病例组合差异。
共有625名患者(哥本哈根297名,伦敦328名)纳入分析。伦敦的大多数患者(85%)入住普通内科病房,其中26%随后转入中风单元。在哥本哈根,57%的患者直接入住中风或神经科病房,其中23%随后转入单独的康复医院。哥本哈根的总住院平均时长多11天。哥本哈根的患者死亡可能性低于伦敦患者;对于脑梗死患者,病例组合调整后的风险比为0.53(95%CI为0.35至0.80)。然而,出血性中风患者在伦敦的死亡比例较低。与伦敦护理模式相比,采用哥本哈根模式的ICER为每获得一个生命年21,579美元至37,444美元,适用于脑梗死患者。
与伦敦护理模式相比,哥本哈根模式的ICER在通常被认为具有成本效益的范围内。