O'Shea J G
Birmingham and Midland Eye Centre, United Kingdom.
Ophthalmic Epidemiol. 2000 Jun;7(2):149-57.
To determine the morbidity of vernal, atopic and other disease mediated by eosinophils amongst the Palestinian Community of East Jerusalem, West Bank and Gaza Strip.
In a prospective outpatient study, 840 people were screened for evidence of eosinophilic external eye disease by history taking and medical examination of the external eye, conjunctiva, nose and paranasal sinuses in the outpatient clinic. The surgical and iatrogenic morbidity of the condition was concurrently estimated, and the prescribing habits of local West Bank ophthalmologists were carefully evaluated. The favoured regime was locally manufactured antihistamine drops, usually in combination with an aminoglycoside antibiotic that characteristically exacerbates the condition. Topical steroids, such as guttae prednisolone forte, were also overused as a modality to treat the condition.
Since the recent decline of endemic trachoma, vernal eye disease is now the leading cause of outpatient ophthalmic morbidity amongst Palestinians of East Jerusalem. The disease accounts for at least 9. 8% of approximately 74,400 annual outpatient attendances to ophthalmic clinics in East Jerusalem, the West Bank and Gaza. The manifestations of the disease, however, are more protean than this. In the context of poor hygiene and sometimes dubious medical practice, vernal eye disease is often responsible for serious anterior segment and external ophthalmic disease.
确定耶路撒冷东部、约旦河西岸和加沙地带的巴勒斯坦社区中春季角结膜炎、特应性疾病及其他嗜酸性粒细胞介导疾病的发病率。
在一项前瞻性门诊研究中，在门诊通过病史采集以及对外眼、结膜、鼻和鼻窦进行医学检查，对840人进行嗜酸性粒细胞性外眼疾病证据的筛查。同时评估该疾病的手术和医源性发病率，并仔细评估约旦河西岸眼科医生的处方习惯。常用的治疗方案是当地生产的抗组胺滴眼液，通常与一种会使病情加重的氨基糖苷类抗生素联合使用。局部用类固醇，如强的松龙滴眼液，也被过度用作治疗该疾病的一种方式。
自地方性沙眼近期发病率下降以来，春季角结膜炎目前是耶路撒冷东部巴勒斯坦人门诊眼科疾病的主要病因。该疾病在耶路撒冷东部、约旦河西岸和加沙地带每年约74400次眼科门诊就诊中至少占9.8%。然而，该疾病的表现更为多样。在卫生条件差且有时医疗行为存疑的情况下，春季角结膜炎常导致严重的眼前段和外眼疾病。
