Dickinson B D, Altman R D, Deitchman S D, Champion H C
Council on Scientific Affairs, American Medical Association, Chicago, IL 60610, USA.
Chest. 2000 Aug;118(2):522-6. doi: 10.1378/chest.118.2.522.
The occasional use of over-the-counter (OTC) epinephrine inhalers appears to be safe and effective when used according to labeled instruction by individuals with mild, intermittent asthma. However, gross misuse of these products can cause severe adverse reactions, including death. Limited survey data suggest that approximately 20% of individuals using OTC epinephrine inhalers have mild-to-moderate persistent asthma. According to recent consensus guidelines, these individuals should be under a physician's care and receiving corticosteroid therapy. If these products continue to be marketed, labeling should be strengthened to better educate users about appropriate and inappropriate use of OTC epinephrine inhalers intended for patients with mild, intermittent asthma.
对于轻度间歇性哮喘患者，按照标签说明偶尔使用非处方（OTC）肾上腺素吸入器似乎是安全有效的。然而，这些产品的严重误用可能会导致严重不良反应，包括死亡。有限的调查数据表明，使用OTC肾上腺素吸入器的个体中约有20%患有轻度至中度持续性哮喘。根据最近的共识指南，这些个体应在医生的护理下并接受皮质类固醇治疗。如果这些产品继续上市销售，应加强标签说明，以便更好地教育使用者如何正确和错误地使用适用于轻度间歇性哮喘患者的OTC肾上腺素吸入器。
