Dilber E, Göçmen A, Kiper N, Ozçelik U
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2000 Apr-Jun;42(2):145-7.
The purpose of this study was to determine the prevalence of anti-tuberculosis drug resistance in children followed at Hacettepe University Ihsan Doğramaci Children's Hospital. Sixty cases with tuberculosis for whom susceptibility testing was available were searched retrospectively. Teh overall drug resistance was 26.7 percent. Resistance to streptomycin (sm) was the most frequent (18.3%), followed by isoniazid (6.7%), rifampicin (6.5%), and ethambutol (4.2%). Strain resistant to more than one drug was present in two cases (3.3%). In summary, excluding SM, both single and multidrug resistance were relatively low in our pediatric patients.
本研究的目的是确定在哈杰泰佩大学伊桑·多格拉马奇儿童医院接受随访的儿童中抗结核药物耐药性的流行情况。对60例有药敏试验结果的结核病患儿进行了回顾性研究。总体耐药率为26.7%。对链霉素(sm)的耐药最为常见(18.3%),其次是异烟肼(6.7%)、利福平(6.5%)和乙胺丁醇(4.2%)。有2例(3.3%)存在对不止一种药物耐药的菌株。总之,除链霉素外,我们的儿科患者中单一和多药耐药性相对较低。