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一名患有急性特发性血小板减少性紫癜且接受类固醇治疗的患者发生沙门氏菌败血症性关节炎。

Salmonella septic arthritis in a patient with acute idiopathic thrombocytopenic purpura treated with steroid.

作者信息

Kanra G, Seçmeer G, Toyran M, Cengiz A B, Değertekin Y, Kara A

机构信息

Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

出版信息

Turk J Pediatr. 2000 Apr-Jun;42(2):151-4.

Abstract

Salmonella has three clinical presentations: self-limiting gastroenteritis, a systemic syndrome (enteric or typhoid fever), and bacteremia with focal infection. Hematogenous infections can cause focal lesions, but unusual manifestations occur more often when predisposing factors such as T cell defect, hemolytic disorders (sickle cell disease, malaria) or trauma are present. Salmonella tend to invade bones and joints. There is no mention of acute idiopathic (immune) thrombocytopenic purpura as a predisposing factor for salmonella septic arthritis; however there are reports about the importance of platelets for the immune response. Here we present a case of Salmonella enteritidis septic arthritis following acute idiopathic (immune) thrombocytopenic purpura in a 15-year-old female patient who has been on steroid therapy for the last two weeks.

摘要

沙门氏菌有三种临床表现

自限性胃肠炎、一种全身性综合征(肠热症或伤寒热)以及伴有局灶性感染的菌血症。血源性感染可导致局灶性病变,但当存在诸如T细胞缺陷、溶血性疾病(镰状细胞病、疟疾)或创伤等易感因素时,不寻常的表现更常出现。沙门氏菌易于侵袭骨骼和关节。没有提及急性特发性(免疫性)血小板减少性紫癜是沙门氏菌性败血症性关节炎的易感因素;然而,有关于血小板对免疫反应重要性的报道。在此,我们报告一例15岁女性患者,在过去两周接受类固醇治疗,患急性特发性(免疫性)血小板减少性紫癜后发生肠炎沙门氏菌败血症性关节炎。

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