Hannu T J, Leirisalo-Repo M
Second Department of Medicine, Helsinki University Central Hospital, Finland.
J Rheumatol. 1988 Nov;15(11):1668-71.
Twenty-three patients with reactive salmonella arthritis were treated at the Departments of Medicine (in 1970-1984) or at the Outpatient Department (in 1980-1986) of Meilahti Hospital. Nine different salmonella species were implicated as triggering factors. Salmonella was detected in 74% of the patients by stool cultures. Widal test was positive (greater than or equal to 1:160) in the remainder. The acute clinical picture was that of oligo or polyarthritis. Other musculoskeletal and inflammatory symptoms were frequent. The mean duration of the acute arthritis was 4.7 months (range 1.5-6.0). In 4 patients the disease ran a chronic course. The treatment of salmonella infection with chemotherapy had no obvious effect on the duration of the arthritis. In conclusion, salmonella arthritis is a form of seronegative spondyloarthritis, with acute features common to other types of reactive arthritides. The search for Salmonella should be included in the study of a patient with acute arthritis. Serology can be of help in patients with negative bacterial cultures.
1970年至1984年期间,梅拉hti医院内科或1980年至1986年期间门诊共收治了23例反应性沙门氏菌关节炎患者。9种不同的沙门氏菌被认为是触发因素。74%的患者通过粪便培养检测出沙门氏菌。其余患者肥达试验呈阳性(大于或等于1:160)。急性临床表现为少关节炎或多关节炎。其他肌肉骨骼和炎症症状很常见。急性关节炎的平均病程为4.7个月(范围1.5 - 6.0个月)。4例患者病情呈慢性病程。用化疗治疗沙门氏菌感染对关节炎的病程没有明显影响。总之,沙门氏菌关节炎是血清阴性脊柱关节炎的一种形式,具有其他类型反应性关节炎常见的急性特征。对急性关节炎患者的研究应包括对沙门氏菌的检测。血清学检查对细菌培养阴性的患者可能有帮助。