Enns M W, Larsen D K, Cox B J
University of Manitoba, Department of Psychiatry, PZ-430 771 Bannatyne Ave., Winnipeg, Manitoba, Canada R3E 3N4.
J Affect Disord. 2000 Oct;60(1):33-41. doi: 10.1016/s0165-0327(99)00156-1.
The observer-rated Hamilton depression scale (HamD) and the self-report Beck Depression Inventory (BDI) are among the most commonly used rating scales for depression, and both have well demonstrated reliability and validity. However, many depressed subjects have discrepant scores on these two assessment methods. The present study evaluated the ability of demographic, clinical and personality factors to account for the discrepancies observed between BDI and HamD ratings.
The study group consisted of 94 SCID-diagnosed outpatients with a current major depressive disorder. Subjects were rated with the 21-item HamD and completed the BDI and the NEO-Five Factor Inventory.
Younger age, higher educational attainment, and depressive subtype (atypical, non-melancholic) were predictive of higher BDI scores relative to HamD observer ratings. In addition, high neuroticism, low extraversion and low agreeableness were associated with higher endorsement of depressive symptoms on the BDI relative to the HamD. In general, these predictive variables showed a greater ability to explain discrepancies between self and observer ratings of psychological symptoms of depression compared to somatic symptoms of depression.
The study does not determine which aspects of neuroticism and extraversion contribute to the observed BDI/HamD discrepancies.
Depression ratings obtained with the BDI and HamD are frequently discordant and a number of patient characteristics robustly predict the discrepancy between these two rating methods. The value of multi-modal assessment in the conduct of research on depressive disorders is re-affirmed.
由观察者评定的汉密尔顿抑郁量表(HamD)和自评的贝克抑郁量表(BDI)是最常用的抑郁评定量表,二者均已充分证明了其可靠性和有效性。然而,许多抑郁症患者在这两种评估方法上的得分存在差异。本研究评估了人口统计学、临床和人格因素对BDI与HamD评分之间差异的解释能力。
研究组由94名经SCID诊断为当前患有重度抑郁症的门诊患者组成。对受试者进行21项HamD评定,并让他们完成BDI和大五人格量表(NEO)。
相对于HamD观察者评分,年龄较小、受教育程度较高以及抑郁亚型(非典型、非忧郁型)可预测BDI得分较高。此外,高神经质、低外向性和低宜人性与BDI上相对于HamD更高的抑郁症状认可程度相关。总体而言,与抑郁的躯体症状相比,这些预测变量在解释抑郁心理症状的自评与观察者评分之间的差异方面表现出更强的能力。
该研究未确定神经质和外向性的哪些方面导致了观察到的BDI/HamD差异。
BDI和HamD获得的抑郁评分经常不一致,许多患者特征有力地预测了这两种评分方法之间的差异。再次肯定了多模式评估在抑郁症研究中的价值。