Bruel H, Guillemant V, Saladin-Thiron C, Chabrolle J P, Lahary A, Poinsot J
Service de médecine néonatale, hôpital Flaubert, Le Havre, France.
Arch Pediatr. 2000 Jul;7(7):745-7. doi: 10.1016/s0929-693x(00)80155-4.
Drug administration during the last trimester of pregnancy may have adverse effects for the newborn.
A hemolytic anemia occurred during the first hours of life in a full-term neonate whose mother had taken nitrofurantoin during the last month of pregnancy.
The immature enzymatic systems of the neonate are exposed to this adverse effect and justify the recommendation not to prescribe nitrofurantoin at the end of pregnancy.
孕期最后三个月用药可能对新生儿产生不良影响。
一名足月新生儿在出生后数小时内发生溶血性贫血，其母亲在孕期最后一个月服用了呋喃妥因。
新生儿未成熟的酶系统易受此不良影响，这证明了孕期末期不建议使用呋喃妥因的合理性。
Zotero 插件