Johnson M D, Kinney M C, Scheithauer B W, Briley R J, Hamilton K, McPherson W F, Barton J H
Department of Pathology, Vanderbilt Medical School and Nashville Veterans Administration Medical Center, Nashville, Tennessee 32732, USA.
Neurosurgery. 2000 Aug;47(2):454-6; discussion 456-7. doi: 10.1097/00006123-200008000-00038.
A rare case of dura-based primary cerebral Hodgkin's disease clinically and radiographically indistinguishable from a meningioma is described.
A 55-year-old immunocompetent woman presented with headaches and ataxia. Magnetic resonance images demonstrated a circumscribed diffusely enhancing mass with a dural tail attached to the cerebellar tentorium.
Operative inspection also suggested a meningioma, but a frozen section of the firm mass revealed an inflammatory lesion. Subsequent pathological analysis demonstrated Hodgkin's disease, nodular sclerosing type. An extensive workup revealed no systemic disease.
This case illustrates the rare occurrence of primary intracranial Hodgkin's disease and its mimicry of meningioma.
本文描述了一例罕见的硬脑膜原发性脑霍奇金淋巴瘤,其临床及影像学表现与脑膜瘤难以区分。
一名55岁免疫功能正常的女性出现头痛和共济失调。磁共振成像显示一个边界清晰、弥漫性强化的肿块,有一个硬膜尾征附着于小脑幕。
手术检查也提示为脑膜瘤,但对质地坚硬的肿块进行冰冻切片显示为炎性病变。随后的病理分析证实为结节硬化型霍奇金淋巴瘤。全面检查未发现全身性疾病。
该病例说明了原发性颅内霍奇金淋巴瘤的罕见性及其对脑膜瘤的模仿。