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老年人阑尾炎

Appendicitis in the elderly.

作者信息

Lee J F, Leow C K, Lau W Y

机构信息

Chinese University of Hong Kong, Department of Surgery, Prince of Wales Hospital, Shatin, Hong Kong.

出版信息

Aust N Z J Surg. 2000 Aug;70(8):593-6. doi: 10.1046/j.1440-1622.2000.01905.x.

DOI:10.1046/j.1440-1622.2000.01905.x
PMID:10945554
Abstract

BACKGROUND

Acute appendicitis in the elderly (i.e. those over 60 years of age) is associated with high morbidity and mortality rates. The present retrospective study reviews 10 years ( 1986-1996) of experience and outcome in treating acute appendicitis in patients aged 60 or above.

METHODS

One hundred and thirty patients with acute appendicitis were identified and their case notes reviewed.

RESULTS

Acute appendicitis was diagnosed at admission in 84 patients (64.6%). The remaining patients were observed for a median duration of 9.4 h prior to diagnosis and treatment. Patients with an underlying perforated acute appendix had a significantly longer period of pain prior to admission (P = 0.029; Mann-Whitney U-test) but perforation per se was not associated with a significantly higher rate of morbidity and longer length of hospital stay. In contrast, the use of midline or paramedian incisions was associated with a higher wound infection rate (P=0.003; Pearson chi-squared test) and a longer hospital stay (P<0.001; Mann Whitney U-test). None of the patients were subsequently found to have an underlying colonic neoplasm. The overall morbidity rate was 28%. The mortality rate was 2.3% and all three patients who died had a severe comorbid medical condition prior to developing acute appendicitis.

CONCLUSIONS

Acute appendicitis in the elderly is still associated with significant morbidity. But once acute appendicitis is diagnosed, then expedient surgery, appropriate use of perioperative antibiotics and a right lower quadrant incision can help to minimize the morbidity. Pre-existing severe comorbid medical condition(s) is a major contributory factor to mortality in these patients.

摘要

背景

老年急性阑尾炎(即60岁以上人群)与高发病率和死亡率相关。本回顾性研究回顾了10年(1986 - 1996年)来60岁及以上患者急性阑尾炎的治疗经验和结果。

方法

确定130例急性阑尾炎患者并查阅其病历。

结果

84例患者(64.6%)在入院时被诊断为急性阑尾炎。其余患者在诊断和治疗前中位观察时间为9.4小时。潜在急性阑尾炎穿孔患者入院前疼痛时间明显更长(P = 0.029;曼-惠特尼U检验),但穿孔本身与明显更高的发病率和更长的住院时间无关。相比之下,采用中线或旁正中切口与更高的伤口感染率(P = 0.003;Pearson卡方检验)和更长的住院时间相关(P < 0.001;曼-惠特尼U检验)。随后未发现患者有潜在的结肠肿瘤。总体发病率为28%。死亡率为2.3%,所有三名死亡患者在发生急性阑尾炎之前都有严重的合并症。

结论

老年急性阑尾炎仍与显著的发病率相关。但一旦诊断为急性阑尾炎,则迅速手术、合理使用围手术期抗生素和右下腹切口有助于将发病率降至最低。既往存在的严重合并症是这些患者死亡的主要促成因素。

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