Symeonidis Nikolaos G, Pavlidis Efstathios T, Psarras Kyriakos K, Stavrati Kalliopi, Nikolaidou Christina, Marneri Alexandra, Geropoulos Georgios, Meitanidou Maria, Andreou Emili, Pavlidis Theodoros E
School of Medicine, Second Surgical Propedeutic Department, Ippokrateio General Hospital, Aristotle University of Thessaloniki, Konstantinoupoleos 49, Thessaloniki 546 42, Greece.
Surg Res Pract. 2022 Mar 31;2022:1836754. doi: 10.1155/2022/1836754. eCollection 2022.
Acute appendicitis is the most common surgical emergency. Early detection of patients with complicated appendicitis leads to prompt surgical management and better outcome. This study investigated the relationship between the severity of acute appendicitis and the presence of preoperative hyponatremia.
We retrospectively reviewed the medical files of adult patients operated on for acute appendicitis over a 6-year period. Hyponatremia was defined as serum sodium level of ≤135 mEq/L. Patients were classified into complicated appendicitis and noncomplicated appendicitis according to operative findings and/or histopathology reports.
A total of 129 patients were identified and included in this study. Complicated appendicitis was found more frequently in female patients and older patients. Hyponatremia was found significantly more frequently in patients with complicated appendicitis ( < 0.001) and also in patients with perforation than without perforation (=0.047).
The present study demonstrated that preoperative hyponatremia is associated with complicated appendicitis. Serum sodium levels, a routine, low-cost laboratory test, could act as an accessory marker aiding surgeons in earlier identification of gangrenous or perforated acute appendicitis.
急性阑尾炎是最常见的外科急症。早期发现复杂性阑尾炎患者可促使及时进行手术治疗并获得更好的预后。本研究调查了急性阑尾炎的严重程度与术前低钠血症之间的关系。
我们回顾性分析了6年间接受急性阑尾炎手术的成年患者的病历。低钠血症定义为血清钠水平≤135 mEq/L。根据手术发现和/或组织病理学报告，将患者分为复杂性阑尾炎和非复杂性阑尾炎。
本研究共纳入129例患者。女性患者和老年患者中复杂性阑尾炎更为常见。复杂性阑尾炎患者中低钠血症的发生率显著更高（<0.001），穿孔患者中低钠血症的发生率也高于未穿孔患者（=0.047）。
本研究表明术前低钠血症与复杂性阑尾炎有关。血清钠水平作为一项常规、低成本的实验室检查，可作为辅助标志物，帮助外科医生更早识别坏疽性或穿孔性急性阑尾炎。
