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对100例连续癌症患者采用头静脉切开法进行慢性留置中心静脉通路的前瞻性分析。

A prospective analysis of the cephalic vein cutdown approach for chronic indwelling central venous access in 100 consecutive cancer patients.

作者信息

Povoski S P

机构信息

Department of Surgery, West Virginia University, Robert C. Byrd Health Science Center, Morgantown 26506, USA.

出版信息

Ann Surg Oncol. 2000 Aug;7(7):496-502. doi: 10.1007/s10434-000-0496-9.

Abstract

BACKGROUND

Chronic indwelling central venous access devices (CICVAD) generally are placed by the percutaneous subclavian vein approach. The cephalic vein cutdown approach is used only infrequently. Although the technique has been well described, few prospective data are available on the cephalic vein cutdown approach.

METHODS

From September 9, 1998, to July 20, 1999, the cephalic vein cutdown approach was attempted in 100 consecutive cancer patients taken to the operating room with the intention of placing CICVAD. Median patient age was 54.5 years (range 18-88), with 46 men and 54 women. Twenty-five patients had gastrointestinal malignancies, 17 had breast cancer, 15 had lymphoma, 13 had lung cancer, 12 had leukemia, 5 had multiple myeloma, and 13 had other malignancies. Patients were followed prospectively for immediate and long-term outcome.

RESULTS

CICVAD placement via the cephalic vein cutdown approach was successful in 82 patients; the remaining 18 patients required conversion to a percutaneous subclavian vein approach. The reasons for inability to place CICVAD via cephalic vein cutdown approach were a cephalic vein that was too small (10 patients), an absent cephalic vein (7 patients), and inability to traverse the angle of insertion of the cephalic vein into the subclavian vein (1 patient). There were 56 subcutaneous ports and 26 tunneled catheters. Median operating time was 44 minutes (range, 26-79 minutes). No postoperative pneumothorax occurred. Median catheter duration was 198 days (range, 0-513 days). Long-term complications included catheter-related bacteremia (6%), site infection (2%), deep venous thrombosis (5%), port pocket hematoma (1%), and superior vena cava stricture (1%). Thirty-seven percent of patients have died since CICVAD placement. Twenty-nine percent of the CICVADs have been removed.

CONCLUSIONS

The cephalic vein cutdown approach was successful in 82% of patients. This approach is a safe and useful alternative to the percutaneous subclavian vein approach.

摘要

背景

长期留置中心静脉通路装置(CICVAD)通常采用经皮锁骨下静脉穿刺法置入。头静脉切开法仅偶尔使用。尽管该技术已有详细描述,但关于头静脉切开法的前瞻性数据却很少。

方法

从1998年9月9日至1999年7月20日,对100例连续的癌症患者尝试采用头静脉切开法置入CICVAD,这些患者均被送往手术室。患者年龄中位数为54.5岁(范围18 - 88岁),其中男性46例,女性54例。25例患者患有胃肠道恶性肿瘤,17例患有乳腺癌,15例患有淋巴瘤,13例患有肺癌,12例患有白血病,5例患有多发性骨髓瘤,13例患有其他恶性肿瘤。对患者进行前瞻性随访以观察近期和远期结局。

结果

82例患者通过头静脉切开法成功置入CICVAD;其余18例患者需要改为经皮锁骨下静脉穿刺法。无法通过头静脉切开法置入CICVAD的原因包括头静脉过小(10例)、头静脉缺如(7例)以及无法穿过头静脉汇入锁骨下静脉的夹角(1例)。共置入56个皮下端口和26根隧道式导管。手术时间中位数为44分钟(范围26 - 79分钟)。术后未发生气胸。导管留置时间中位数为198天(范围0 - 513天)。远期并发症包括导管相关菌血症(6%)、局部感染(2%)、深静脉血栓形成(5%)、端口周围血肿(1%)和上腔静脉狭窄(1%)。自CICVAD置入以来,37%的患者已死亡。29%的CICVAD已被拔除。

结论

头静脉切开法在82%的患者中取得成功。该方法是经皮锁骨下静脉穿刺法的一种安全且有用的替代方法。

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