Pradier C, Keita-Perse O, Bernard E, Gisbert C, Vezolles M J, Armengaud A, Carles D, Grimont F, Desenclos J C, Dellamonica P
Fédération des Maladies Transmissibles, Hôpital l'Archet, Nice, France.
Eur J Clin Microbiol Infect Dis. 2000 Jun;19(6):464-7. doi: 10.1007/s100960000300.
A case-control study was conducted to establish the source of a community outbreak of typhoid fever in Utelle, France, a village located in the Alpes-Maritimes district of the French Riviera. Thirteen confirmed cases of typhoid fever and 41 confirmed community controls were included in the study. Cases and controls did not differ regarding ingestion of water. Multivariate logistic regression analysis identified consumption of pork meats during a village festival as the only statistically significant risk factor for typhoid fever after adjusting for age and sex (odds ratio, 76.0; 95% confidence interval, 3.5-1660). Assessment of food-handling procedures at the inn where the food had been prepared showed that the refrigeration and cooking facilities were inadequate to maintain a proper sanitary environment during the preparation of a meal for 350 people. Although the exact cause of the epidemic could not be confirmed, food contaminated by a chronic typhi carrier is the most plausible hypothesis.
开展了一项病例对照研究,以确定法国滨海阿尔卑斯省(位于法国里维埃拉地区)乌泰勒村伤寒社区暴发的源头。该研究纳入了13例确诊伤寒病例和41例确诊的社区对照。病例组和对照组在饮水摄入方面没有差异。多因素逻辑回归分析显示,在调整年龄和性别后,乡村节日期间食用猪肉是伤寒唯一具有统计学意义的危险因素(比值比为76.0;95%置信区间为3.5-1660)。对提供食物的小旅馆食品处理程序的评估表明,在为350人准备餐食期间,制冷和烹饪设施不足以维持适当的卫生环境。尽管无法确定疫情的确切原因,但最合理的假设是食物被慢性伤寒携带者污染。