Magalhaes R L, Braun W E, Straffon R A, Hoffman G C, Shainoff J R, Osborne G, Deodhar S D
Am J Med. 1975 Jun;58(6):862-8. doi: 10.1016/0002-9343(75)90643-9.
The development of microangiopathic hemolytic anemia after renal transplantation in a 17 year old white boy is reported, and the literature is reviewed. In this patient microangiopathic hemolytic anemia developed 6 weeks after renal transplantation during a second episode of rejection. Light, fluorescence and electron microscopy demonstrated the renal vascular lesion associated with this syndrome. In contrast to the other four previously reported cases of microangiopathic hemolytic anemia associated with renal allotransplantation, this patient had complete resolution of the microangiopathic hemolytic anemia with heparin therapy and improved allograft function, presumably with diminution of the vascular lesion. He survived a complicated early period after renal transplantation and has shown no recurrence of microangiopathic hemolytic anemia in the 18 months since transplantation. Special red blood cell and fibrinogen studies are discussed.
报道了一名17岁白人男孩肾移植后微血管病性溶血性贫血的发生情况，并对相关文献进行了综述。该患者在肾移植6周后、第二次排斥反应期间发生了微血管病性溶血性贫血。光镜、荧光镜和电镜检查显示了与该综合征相关的肾血管病变。与之前报道的另外4例与同种异体肾移植相关的微血管病性溶血性贫血病例不同，该患者经肝素治疗后微血管病性溶血性贫血完全缓解，移植肾功能改善，推测血管病变减轻。他在肾移植后的早期并发症期存活下来，移植后18个月未出现微血管病性溶血性贫血复发。文中还讨论了特殊的红细胞和纤维蛋白原研究。
