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自体骨髓移植后微血管病性溶血性贫血和肾功能损害:溶血尿毒综合征病例?

Microangiopathic hemolytic anemia and renal impairment following autologous bone marrow transplantation: a case of hemolytic uremic syndrome?

作者信息

Wassmann B, Martin H, Elsner S, Bruecher J, Thaiss F, Stahl R A, Hoelzer D

机构信息

Department of Hematology, Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.

出版信息

Bone Marrow Transplant. 1994 Nov;14(5):849-51.

PMID:7889019
Abstract

Thrombotic microangiopathy, which encompasses both thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS), is a severe and life-threatening complication following bone marrow transplantation (BMT). It has been reported after allogeneic BMT but may also occur after autologous BMT. Here we describe a case of microangiopathic hemolytic anemia and progressive renal failure subsequent to autologous BMT.

摘要

血栓性微血管病,包括血栓性血小板减少性紫癜(TTP)和溶血尿毒综合征(HUS),是骨髓移植(BMT)后一种严重且危及生命的并发症。它在异基因BMT后已有报道,但也可能发生在自体BMT后。在此,我们描述一例自体BMT后发生微血管病性溶血性贫血和进行性肾衰竭的病例。

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