Nesher G
Department of Internal Medicine, Rheumatology Service, Shaare-Zedek Medical Center, Jerusalem, Israel.
Clin Exp Rheumatol. 2000 Jul-Aug;18(4 Suppl 20):S24-6.
Neurological manifestations are common in giant cell arteritis. Both the central and peripheral nervous system can be involved. The most dreaded manifestations are visual loss and stroke. Both frequently have premonitory symptoms, such as amaurosis fugax, blurry vision, diplopia, transient ischemic attacks, and jaw claudication. Although most of these manifestations occur prior to steroid therapy, they may also develop during the early phase of therapy, or during tapering of the dose of steroids. Earlier diagnosis, close monitoring and improving the treatment protocols may prevent mortality and improve morbidity in these cases.
神经系统表现在巨细胞动脉炎中很常见。中枢神经系统和周围神经系统均可受累。最可怕的表现是视力丧失和中风。两者通常都有先兆症状，如一过性黑矇、视力模糊、复视、短暂性脑缺血发作和颌部跛行。尽管这些表现大多发生在使用类固醇治疗之前，但也可能在治疗早期或类固醇剂量逐渐减少期间出现。早期诊断、密切监测并改进治疗方案可能会降低这些病例的死亡率并改善发病率。
