Suppr超能文献

巨细胞动脉炎并发舌坏死和双侧小脑缺血性脑卒中。

Giant cell arteritis complicated by tongue necrosis and bilateral cerebellar ischaemic stroke.

机构信息

Department of Rheumatology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Department of Neurology, University Hospital Southampton NHS Foundation Trust, Southampton, UK

出版信息

BMJ Case Rep. 2021 Dec 8;14(12):e244948. doi: 10.1136/bcr-2021-244948.

Abstract

Giant cell arteritis (GCA) typically presents with headache, scalp tenderness or visual disturbance. Other symptoms include orofacial pain, constitutional symptoms and ischaemic stroke. An 81-year-old woman with a background of type-2 diabetes and hypertension presented with headache, oral pain and right visual loss. Examination showed hypertension, nodular temporal arteries, reduced visual acuity and suspected oral candida. Inflammatory markers were raised and she was diagnosed with GCA and commenced on corticosteroids. During treatment she developed tongue ulceration, then acute vertigo and incoordination with nystagmus and ataxia. Neuroimaging confirmed bilateral, cerebellar ischaemic strokes and temporal artery biopsy was consistent with GCA. With corticosteroids and secondary prevention of stroke measures she is now functionally independent. Oral pain is an uncommon symptom of GCA and delays in recognition may lead to catastrophic consequences. Clinicians should be aware of uncommon presentations and to optimise additional ischaemic stroke risk-factors.

摘要

巨细胞动脉炎(GCA)通常表现为头痛、头皮触痛或视觉障碍。其他症状包括口面疼痛、全身症状和缺血性脑卒中。一位 81 岁的女性,有 2 型糖尿病和高血压病史,表现为头痛、口腔疼痛和右眼视力丧失。检查发现高血压、颞动脉结节、视力下降和疑似口腔念珠菌病。炎症标志物升高,诊断为 GCA,并开始使用皮质类固醇治疗。在治疗过程中,她出现了舌溃疡,然后出现急性眩晕、眼球震颤和共济失调。神经影像学证实为双侧小脑缺血性脑卒中,颞动脉活检符合 GCA。通过皮质类固醇和脑卒中二级预防措施,她现在功能独立。口腔疼痛是 GCA 的一种不常见症状,延迟识别可能导致灾难性后果。临床医生应注意不常见的表现,并优化其他缺血性脑卒中风险因素。

相似文献

1
Giant cell arteritis complicated by tongue necrosis and bilateral cerebellar ischaemic stroke.
BMJ Case Rep. 2021 Dec 8;14(12):e244948. doi: 10.1136/bcr-2021-244948.
2
Tongue necrosis secondary to giant cell arteritis.
BMJ Case Rep. 2023 May 16;16(5):e254888. doi: 10.1136/bcr-2023-254888.
3
Bilateral Scalp Necrosis in Giant Cell Arteritis.
J Neuroophthalmol. 2021 Mar 1;41(1):e125-e127. doi: 10.1097/WNO.0000000000000862.
5
Temporal artery ultrasonography for the diagnosis of giant cell arteritis: a case report.
Quintessence Int. 2024 Apr 25;55(4):336-343. doi: 10.3290/j.qi.b4938419.
7
A 78-year-old female with severe tongue pain: benefit of modern ultrasound.
BMC Med Imaging. 2021 Mar 20;21(1):55. doi: 10.1186/s12880-021-00585-5.
8
Stroke as an atypical initial presentation of giant cell arteritis.
BMC Geriatr. 2018 Feb 21;18(1):55. doi: 10.1186/s12877-018-0738-y.
9
Tongue necrosis secondary to giant cell arteritis, successfully treated with tocilizumab: a case report.
BMC Musculoskelet Disord. 2023 May 15;24(1):382. doi: 10.1186/s12891-023-06465-z.
10
Anterior ischemic optic neuropathy due to giant cell arteritis with normal inflammatory markers.
Graefes Arch Clin Exp Ophthalmol. 2008 Jun;246(6):913-5. doi: 10.1007/s00417-007-0762-7. Epub 2008 Apr 2.

引用本文的文献

1
Lingual necrosis in giant-cell arteritis: a case-based review.
Rheumatol Int. 2025 Sep 12;45(10):226. doi: 10.1007/s00296-025-05969-2.
2
Lingual Necrosis in the Setting of Giant Cell Arteritis.
Cureus. 2024 Nov 23;16(11):e74316. doi: 10.7759/cureus.74316. eCollection 2024 Nov.
3
Tongue necrosis secondary to giant cell arteritis, successfully treated with tocilizumab: a case report.
BMC Musculoskelet Disord. 2023 May 15;24(1):382. doi: 10.1186/s12891-023-06465-z.

本文引用的文献

1
Facial Pain: A Comprehensive Review and Proposal for a Pragmatic Diagnostic Approach.
Eur Neurol. 2020;83(1):5-16. doi: 10.1159/000505727. Epub 2020 Mar 27.
2
British Society for Rheumatology guideline on diagnosis and treatment of giant cell arteritis.
Rheumatology (Oxford). 2020 Mar 1;59(3):e1-e23. doi: 10.1093/rheumatology/kez672.
4
Hypertension and Stroke: Update on Treatment.
Eur Cardiol. 2019 Jul 11;14(2):111-115. doi: 10.15420/ecr.2019.11.1. eCollection 2019 Jul.
5
Giant cell arteritis: is the clinical spectrum of the disease changing?
BMC Geriatr. 2019 Jul 29;19(1):200. doi: 10.1186/s12877-019-1225-9.
7
Delayed Diagnosis of Giant Cell Arteritis in the Setting of Isolated Lingual Necrosis.
Clin Med Insights Case Rep. 2019 Jun 20;12:1179547619857690. doi: 10.1177/1179547619857690. eCollection 2019.
8
Giant cell arteritis: early diagnosis is key.
Eye Brain. 2019 Jan 17;11:1-12. doi: 10.2147/EB.S170388. eCollection 2019.
9
Current and emerging diagnosis tools and therapeutics for giant cell arteritis.
Expert Rev Clin Immunol. 2018 Jul;14(7):593-605. doi: 10.1080/1744666X.2018.1485491. Epub 2018 Jun 20.
10
Tongue Necrosis Secondary to Giant Cell Arteritis: A Case Report and Literature Review.
Case Rep Med. 2017;2017:6327437. doi: 10.1155/2017/6327437. Epub 2017 Mar 23.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验