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非特异性尿道炎与四环素类药物

Non-specific urethritis and the tetracyclines.

作者信息

Grimble A S, Amarasuriya K L

出版信息

Br J Vener Dis. 1975 Jun;51(3):198-205. doi: 10.1136/sti.51.3.198.

DOI:10.1136/sti.51.3.198
PMID:1095144
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1045152/
Abstract

The possible aetiological factors in non-gonococcal and non-specific urethritis are reviewed. The response of NSU to various courses of different tetracycline drugs is assessed. Prolonged courses of treatment did not give better results than shorter courses. When reviewing the infective aetiology of non-gonococcal urethritis, it was noted that more than one organism (or potential pathogen) would be present in many cases. It is therefore surmised that there may be at times a mixed aetiology and at other times a truly non-specific aetiology. Isolations by different workers have indicated that the following organisms might be expected: Chlamydia 40 per cent.; Mycoplasma-M. hominis 20 per cent., T-strain over 60 per cent.; Trichomonas 15 per cent.; Candida possibly over 5 per cent. Truly non-specific urethritis may account for 25 to 30 per cent. of cases.

摘要

本文综述了非淋菌性和非特异性尿道炎可能的病因。评估了非特异性尿道炎(NSU)对不同四环素类药物各种疗程的反应。延长疗程并未比短疗程取得更好的效果。在回顾非淋菌性尿道炎的感染病因时,注意到在许多病例中会存在不止一种病原体(或潜在病原体)。因此推测,有时可能是混合病因,有时则是真正的非特异性病因。不同研究人员的分离结果表明,可能会分离出以下病原体:衣原体40%;支原体——人型支原体20%,T株超过60%;滴虫15%;念珠菌可能超过5%。真正的非特异性尿道炎可能占病例的25%至30%。

相似文献

1
Non-specific urethritis and the tetracyclines.非特异性尿道炎与四环素类药物
Br J Vener Dis. 1975 Jun;51(3):198-205. doi: 10.1136/sti.51.3.198.
2
Non-specific urethritis. A placebo-controlled trial of minocycline in conjunction with laboratory investigations.非特异性尿道炎。米诺环素的安慰剂对照试验及实验室研究。
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T-strain mycoplasma in non-gonococcal urethritis. Pathogen or commensal?非淋菌性尿道炎中的T株支原体。病原体还是共生菌?
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Nonspecific urethritis.非特异性尿道炎
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[Role of Chlamydia, Mycoplasmataceae and Trichomonas vaginalis in non-gonococcal urethritis in men].
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Etiology of nongonococcal urethritis.非淋菌性尿道炎的病因
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引用本文的文献

1
Treatment of nongonococcal urethritis with trimethoprim-sulphadiazine and with placebo. A double-blind partner-controlled study.用甲氧苄啶-磺胺嘧啶和安慰剂治疗非淋菌性尿道炎。一项双盲伴侣对照研究。
Br J Vener Dis. 1980 Apr;56(2):101-4. doi: 10.1136/sti.56.2.101.
2
Effect of short term treatment of non-gonococcal urethritis with minocycline.米诺环素短期治疗非淋菌性尿道炎的效果
Genitourin Med. 1986 Feb;62(1):19-23. doi: 10.1136/sti.62.1.19.
3
Tetracycline treatment for non-specific urethritis.四环素治疗非特异性尿道炎。
Br J Vener Dis. 1977 Aug;53(4):230-2. doi: 10.1136/sti.53.4.230.
4
Tetracycline treatment for non-specific urethritis.四环素治疗非特异性尿道炎。
Br J Vener Dis. 1978 Jun;54(3):205-6. doi: 10.1136/sti.54.3.205.
5
Diagnostic, treatment, and reporting criteria for non-specific genital infection in sexually transmitted disease clinics in England and Wales. 2: Treatment and reporting criteria.英格兰和威尔士性传播疾病诊所非特异性生殖器感染的诊断、治疗及报告标准。2:治疗及报告标准。
Br J Vener Dis. 1978 Dec;54(6):428-32. doi: 10.1136/sti.54.6.428.

本文引用的文献

1
Female consorts of men with non-gonococcal urethritis.非淋菌性尿道炎男性患者的女性配偶
Br J Vener Dis. 1959 Dec;35(4):245-8. doi: 10.1136/sti.35.4.245.
2
AN ALLERGIC BASIS FOR NON-SPECIFIC URETHRITIS.非特异性尿道炎的过敏基础
Br J Vener Dis. 1965 Jun;41(2):107-16. doi: 10.1136/sti.41.2.107.
3
Urogenital trichomoniasis in the male: review of the literature and report on treatment of 37 patients by a new nitroimidazole derivative (Flagyl).男性泌尿生殖系统滴虫病:文献综述及一种新型硝基咪唑衍生物(灭滴灵)治疗37例患者的报告
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PPLO of human genital origin; serological classification of strains and antibody distribution in man.源自人类生殖器的类胸膜肺炎微生物;菌株的血清学分类及人类抗体分布
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Pleuropneumonia-like organisms in genital infections.生殖器感染中的类胸膜肺炎微生物。
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Evaluation of therapy in non-specific urethritis.非特异性尿道炎的治疗评估
Br J Vener Dis. 1958 Jun;34(2):107-12. doi: 10.1136/sti.34.2.107.
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Acute hemorrhagic cystitis; an infection associated with pleuropneumonia-like organisms and related to urethritis and prostatitis.
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Trichomonas vaginalis in urethritis of the male.男性尿道炎中的阴道毛滴虫
Br J Vener Dis. 1956 Dec;32(4):233-5. doi: 10.1136/sti.32.4.233.
9
Occurrence and ecology of Mycoplasma species (pleuropneumonia-like organisms) in the male urethra.男性尿道中支原体属(类胸膜肺炎微生物)的发生情况及生态学
Br J Vener Dis. 1956 Sep;32(3):188-94. doi: 10.1136/sti.32.3.188.
10
Human infection with pleuropneumonia-like organisms.
Lancet. 1955 Feb 5;268(6858):276-9. doi: 10.1016/s0140-6736(55)90107-0.