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[孕期致畸物]

[Teratogens during pregnancy].

作者信息

Jancárková N, Gregor V

机构信息

Gynek.-porod. klinika 1. LF UK a VFN, Praha.

出版信息

Ceska Gynekol. 2000 May;65(3):188-94.

PMID:10953498
Abstract

OBJECTIVE

To sum up the knowledge of the influence of substances in the external environment on the development of the human embryo/fetus during exposure at various periods of intrauterine life.

TYPE OF STUDY

Summary.

SETTING

Department of Obstetrics and Gynecology, 1st Faculty of Medicine, Charles University, Prague.

METHODS

Compilation of data from scientific literature.

RESULTS

An overview of the main groups of teratogenic substances among the physical, chemical, biological and metabolic teratogens. Their relationship to morphological malformations, anomalies and functional defects are described.

CONCLUSION

A summary of the principles/basics of care of a pregnant woman using medication before or during pregnancy and the possibility of evaluating the individual reproductive risk during preconception and prenatal exposure to teratogenic substances.

摘要

目的

总结关于外部环境中的物质在子宫内生活的不同时期暴露时对人类胚胎/胎儿发育影响的知识。

研究类型

综述。

研究地点

布拉格查理大学医学院第一附属医院妇产科。

方法

从科学文献中汇编数据。

结果

概述物理、化学、生物和代谢致畸物中的主要致畸物质类别。描述了它们与形态畸形、异常和功能缺陷的关系。

结论

总结孕妇在怀孕前或怀孕期间用药的护理原则/基本要点,以及在孕前和产前暴露于致畸物质时评估个体生殖风险的可能性。

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