Scott C A, Fish D R
Sir Jules Thorn Telemetry Unit, The National Hospital for Neurology and Neurosurgery, London, England.
Epileptic Disord. 2000 Jun;2(2):89-92.
Literature review shows many anecdotal case reports of cardiac asystole in ictal recordings of partial seizures. We have reviewed our data from the last five years, of patients who are being assessed for epilepsy surgery and found 2 out of more than 1,500 complex partial seizures, recorded in 589 consecutive patients, showing a significant period of asystole (13 and 15 seconds). Our previous studies of cardiac and respiratory parameters during partial seizures showed that a central apnoea occurred in 39%. It is probable that sudden death during seizures is due to the interaction of both cardiac and respiratory irregularities. Although rare (occurrence < 0.15%), the possibility of cardiac asystole occurring in an epilepsy monitoring unit highlights the need for resuscitation equipment to be readily available and for trained nursing staff. Furthermore, it is important to recognize that the semiology of seizures may be affected by the consequences of secondary cardiac asystole.
文献综述显示，在部分性癫痫发作的发作期记录中有许多关于心搏骤停的轶事性病例报告。我们回顾了过去五年中正在接受癫痫手术评估的患者的数据，发现在连续589例患者记录的1500多次复杂部分性发作中，有2次出现了显著的心搏停止期（13秒和15秒）。我们之前对部分性癫痫发作期间心脏和呼吸参数的研究表明，39%的患者出现了中枢性呼吸暂停。癫痫发作期间的猝死很可能是心脏和呼吸异常共同作用的结果。虽然罕见（发生率<0.15%），但癫痫监测单元中出现心搏骤停的可能性凸显了随时准备好复苏设备和训练有素的护理人员的必要性。此外，重要的是要认识到癫痫发作的症状学可能会受到继发性心搏骤停后果的影响。
