Adhiyaman V, Asghar M, White A D
Department of Geriatric Medicine, Wrexham Maelor Hospital, Wrexham, Clwyd, UK.
Int J Clin Pract. 2000 Jun;54(5):338-9.
Upper gastrointestinal tract complications due to non-steroidal anti-inflammatory drugs are well recognised. However, adverse effects on large intestinal mucosa are less common and less well recognised, even though they carry a significant morbidity and mortality. Here we report a case of colonic perforation in a healthy woman without any underlying colonic pathology associated with ingestion of slow release diclofenac sodium.