Schiffmann L, Kahrau S, Berger G, Buhr H J
Department of General, Vascular and Thoracic Surgery, Charite, University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany.
ANZ J Surg. 2005 Aug;75(8):726-7. doi: 10.1111/j.1445-2197.2005.03495.x.
Chronic intake of non-steroidal anti-inflammatory drugs (NSAIDs) has been reported to cause side-effects distal to the duodenum. These include strictures, diaphragm-like lesions and perforations of the small and large intestines. This is the first case report on colon perforation occurring in an adolescent (16-year-old girl) after short-term diclofenac intake.