Knothe H, Wiedemann B
Int J Clin Pharmacol Biopharm. 1975 Mar;11(2):126-31.
In this report it was tried to emphasize several microbiological aspects of the amino-penicillin. Hereby it turns out that the activity differences of all the substances are very similar on microbiological part. A break of the cross-resistance does not happen with all the amino-penicillins. With regard to the appearance of resistant strains, it can be told that the conditions still are advantageous on non-hospitalized patients in the totality. In the clinic a high part of resistant strains are found on different grounds.
在本报告中,试图强调氨基青霉素的几个微生物学方面。由此发现,所有物质在微生物学方面的活性差异非常相似。并非所有氨基青霉素都会出现交叉耐药性的中断。关于耐药菌株的出现,可以说总体上非住院患者的情况仍然有利。在临床上,由于不同原因发现了很大比例的耐药菌株。