Gogate PR, Beenackers AA, Pandit AB
Division of Chemical Engineering, University Department of Chemical Technology, University of Mumbai, Matunga, -400019, Mumbai, India
Biochem Eng J. 2000 Oct 1;6(2):109-144. doi: 10.1016/s1369-703x(00)00081-4.
The multiple-impeller agitated systems are compared with single-impeller agitated systems with a special focus on its applications for bioreactors. Correlations reported in the literature for gas phase hold-up, mass transfer coefficient and power consumption under gassed and ungassed conditions are compared and recommendations have been made regarding their suitability for design and scale-up of bioreactors. The multiple-impeller systems are found to be superior as compared to single-impeller systems in all the above mentioned aspects, except liquid mixing. For all kinds of reactors where the sole purpose is mass transfer, multiple-impeller systems are advantageous and there would be large savings on an industrial scale, especially for the bioreactors where the reaction periods are long and the power consumption cost could be a significant component to the overall production costs.
将多叶轮搅拌系统与单叶轮搅拌系统进行了比较，特别关注其在生物反应器中的应用。比较了文献中报道的气相持液率、传质系数以及通气和不通气条件下的功耗，并就它们对生物反应器设计和放大的适用性提出了建议。结果发现，除液体混合外，在上述所有方面，多叶轮系统均优于单叶轮系统。对于所有以传质为唯一目的的反应器，多叶轮系统具有优势，在工业规模上可节省大量成本，特别是对于反应周期长且功耗成本可能占总生产成本很大一部分的生物反应器。
