De Gennaro L, Ferrara M, Bertini M
Dipartimento di Psicologia-Sezione di Neuroscienze, Università degli Studi 'La Sapienza', Via dei Marsi, 78; 00185, Roma, Italy.
Neurosci Lett. 2000 Sep 8;291(1):41-3. doi: 10.1016/s0304-3940(00)01366-5.
The hypothesis that K-complexes (KCs) contribute to the process of synchronization leading to Slow-Wave Sleep (SWS) was evaluated by measuring their dynamic evolution across sleep cycles and before transitions to rapid eye movement (REM) or to SWS. KC density and inter-KC intervals respectively decreased and increased across the sleep cycles, revealing linear trends. Comparisons among transitions from stage 2 to SWS or to REM sleep showed a prevalence of KCs before the shift to SWS as compared to REM. Changes in KC density before the shift to SWS were fitted by a linear regression, at variance with the transition to REM sleep. Intra-night variations of KCs, paralleling the well-known decrease of slow waves across sleep cycles, and intracycle variations before shifting to SWS, both converge to indicate that KCs can be considered as the forerunner of delta waves.
通过测量K复合波（KCs）在睡眠周期以及向快速眼动（REM）或慢波睡眠（SWS）转变之前的动态变化，对KCs有助于同步过程并导致慢波睡眠这一假设进行了评估。KCs密度和KCs之间的间隔在睡眠周期中分别降低和增加，呈现出线性趋势。从第2阶段向SWS或REM睡眠转变的比较表明，与向REM睡眠转变相比，向SWS转变之前KCs更为普遍。向SWS转变之前KCs密度的变化通过线性回归拟合，这与向REM睡眠的转变不同。KCs的夜间变化与睡眠周期中慢波的众所周知的减少平行，以及向SWS转变之前的周期内变化，都表明KCs可被视为δ波的先驱。
