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超声引导下经皮腹膜活检诊断结核性腹膜炎1例

[A case of tuberculous peritonitis diagnosed by ultrasonography-guide peritoneal biopsy].

作者信息

Mizunoe S, Morinaga R, Umeki K, Yamagata E, Hiramatsu K, Yamakami Y, Yamasaki T, Nagai H, Murakami K, Kashima K, Nasu M

机构信息

Second Department of Internal Medicine, Oita Medical University.

出版信息

Kansenshogaku Zasshi. 2000 Jul;74(7):589-93. doi: 10.11150/kansenshogakuzasshi1970.74.589.

Abstract

The diagnosis of tuberculous peritonitis is quite difficult because the symptoms are not specific for the disease and the incidence of occurrence are relatively rare. We report a case of tuberculous peritonitis diagnosed by ultrasonography-guided peritoneal biopsy. A 64-year-old male was admitted to our hospital because of fever, dyspnea and abdominal pain. Laboratory findings revealed an elevated ESR (53 mm/1 hr.) and positive CRP. The tuberculin skin test was negative. The chest radiograph revealed bilateral pleural effusion. Abdominal ultrasonographic examination and computed tomography showed ascitic fluid, thickening of the mesentery and peritoneum, and inflammatory pseudotumor of the omentum. Ascitic fluid was exudate with a high lymphocyte count and elevated ADA (184 IU/l). Microbiological studies with the fluid were negative. Peritoneal biopsy guided by ultrasonography was performed, and the specimens showed central caseous necrosis surrounded by epitheloid cells and acid-fast bacilli were demonstrated. The size of the pseudotumor, pleural effusion and ascites decreased after antituberculous chemotherapy with corticosteroid was given. Diagnosis of tuberculous peritonitis has often been made by laparotomy or laparoscopy. In a case of this kind, percutaneous peritoneal biopsy guided by ultrasonography is safe and useful.

摘要

结核性腹膜炎的诊断相当困难,因为其症状不具有特异性,且发病率相对较低。我们报告一例通过超声引导下经皮腹膜活检确诊的结核性腹膜炎病例。一名64岁男性因发热、呼吸困难和腹痛入院。实验室检查显示血沉升高(53mm/1小时),C反应蛋白阳性。结核菌素皮肤试验阴性。胸部X线片显示双侧胸腔积液。腹部超声检查和计算机断层扫描显示有腹水、肠系膜和腹膜增厚以及大网膜炎性假瘤。腹水为渗出液,淋巴细胞计数高,腺苷脱氨酶升高(184IU/L)。腹水微生物学检查为阴性。在超声引导下进行了腹膜活检,标本显示中央干酪样坏死,周围有上皮样细胞,并发现抗酸杆菌。给予抗结核化疗加用皮质类固醇后,假瘤、胸腔积液和腹水的大小均减小。结核性腹膜炎的诊断通常通过剖腹手术或腹腔镜检查做出。在这种情况下,超声引导下经皮腹膜活检安全且有用。

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