Hedenstierna G, Edmark L, Aherdan K K
Department of Medical Sciences, Clinical Physiology, University Hospital, Uppsala, Sweden.
Minerva Anestesiol. 2000 May;66(5):293-6.
Atelectasis is a frequent finding in paralysed and mechanically ventilated patients. Atelectasis, causing shunt, impairs oxygenation and could contribute to postoperative pulmonary complications. Pre-oxygenation used during anaesthesia induction causes atelectasis. A lowering of oxygen fraction from 100% to 80% does not shorten the safety time of apnoea period, particularly useful for a difficult intubation, but it reduces drastically the atelectasis incidence.
肺不张在麻痹和机械通气的患者中很常见。肺不张会导致分流,损害氧合,并可能导致术后肺部并发症。麻醉诱导期间使用的预给氧会导致肺不张。将氧分数从100%降至80%并不会缩短呼吸暂停期的安全时间,这对困难插管特别有用,但它会大幅降低肺不张的发生率。