Lyczak J B, Cannon C L, Pier G B
The Channing Laboratory, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.
Microbes Infect. 2000 Jul;2(9):1051-60. doi: 10.1016/s1286-4579(00)01259-4.
Pseudomonas aeruginosa is an ubiquitous pathogen capable of infecting virtually all tissues. A large variety of virulence factors contribute to its importance in burn wounds, lung infection and eye infection. Prominent factors include pili, flagella, lipopolysaccharide, proteases, quorum sensing, exotoxin A and exoenzymes secreted by the type III secretion system.
铜绿假单胞菌是一种无处不在的病原体,几乎能够感染所有组织。多种毒力因子导致其在烧伤创面、肺部感染和眼部感染中具有重要影响。主要因素包括菌毛、鞭毛、脂多糖、蛋白酶、群体感应、外毒素A以及由III型分泌系统分泌的外酶。