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格列本脲诱发类似原发性胆汁性肝硬化的慢性胆汁淤积:一例报告

Glibenclamide induced chronic cholestasis simulating primary biliary cirrhosis: a case report.

作者信息

Ramanathan M, Wahinuddin S, Kew S T

机构信息

Department of Medicine, Taiping Hospital, Perak.

出版信息

Med J Malaysia. 1996 Mar;51(1):140-3.

PMID:10967995
Abstract

A 43-year-old lady with long standing non-insulin dependent diabetes mellitus on glibenclamide presented with cholestatic liver disease. Initially she was thought to have developed primary biliary cirrhosis (PBC). When she made a spontaneous recovery following the withdrawal of glibenclamide, it became obvious that the patient had been suffering from drug-induced chronic cholestasis (DICC). The subtle differences between PBC and DICC are highlighted.

摘要

一位43岁长期服用格列本脲的非胰岛素依赖型糖尿病女性患者出现胆汁淤积性肝病。起初,她被认为患有原发性胆汁性肝硬化(PBC)。当她在停用格列本脲后自发康复时,很明显该患者一直患有药物性慢性胆汁淤积(DICC)。文中强调了PBC和DICC之间的细微差异。

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