琼脂在早产儿高胆红素血症治疗中的应用
Agar in the management of hyperbilirubinaemia in the premature baby.
作者信息
Romagnoli C, Polidori G, Foschini M, Cataldi L, De Turris P, Tortorolo G, Mastrangelo R
出版信息
Arch Dis Child. 1975 Mar;50(3):202-4. doi: 10.1136/adc.50.3.202.
Eighty low birthweight infants (1500 to 2500 g) were randomly assigned to a group given oral agar and a control group. The study was first performed in 24 agar-fed babies and 24 control babies. The treated infants received a daily total amount of 600 mg/kg of agar beginning at 12 hours of age, for 7 days. In the later stage of the trial, 16 agar-fed babies and 16 control babies were investigated. The total daily amount of agar was raised to 700 mg/kg, beginning at 6 hours of age for 7 days. No complications were observed with the administration of agar. Serum bilirubin levels were not significantly lower in the agar-fed infants. We conclude that agar supplemented feeding is not indicated in the management of hyperbilirubinaemia in low birthweight newborn infants.
80名低体重婴儿（1500至2500克）被随机分为口服琼脂组和对照组。该研究首先在24名喂食琼脂的婴儿和24名对照婴儿中进行。接受治疗的婴儿从出生12小时起，每天接受总量为600毫克/千克的琼脂，持续7天。在试验后期，对16名喂食琼脂的婴儿和16名对照婴儿进行了调查。琼脂的每日总量从出生6小时起提高到700毫克/千克，持续7天。服用琼脂未观察到并发症。喂食琼脂的婴儿血清胆红素水平没有显著降低。我们得出结论，在低体重新生儿高胆红素血症的管理中，不建议补充琼脂喂养。
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