Nakayama K, Awata S, Zhang J, Ebinuma H, Mariyama T, Kodama H
Department of Chemistry, Kochi Medical School, Kohasu, Oko-cho, Nankoku-shi, Kochi 783-8505, Japan.
Physiol Chem Phys Med NMR. 2000;32(1):21-6.
The concentrations of sulfur-containing amino acids, taurine, cystathionine, methionine and cystine, as well as cystathionine beta-synthase and gamma-lyase activities in various tissues of Agkistrodon blomhoffi (mamushi) were measured. The concentration of taurine in examined tissues was greater than the concentration of other sulfur-containing amino acids. The concentration of cystathionine in various tissues was also much higher than those of methionine and cystine, but the concentration of cystathionine in the brain was lower than that of methionine. In all tissues examined in this study, cystathionine beta-synthase activity was much higher than that of cystathionine gamma-lyase. The ratios of cystathionine beta-synthase to gamma-lyase activities in various tissues were 5.6 to approximately 85.6. The concentration of sulfur-containing amino acids in muscle and skin divided into eight portions of the body were also determined. The concentrations of methionine and cystine in each portion of muscle and skin were almost the same, but the concentrations of taurine and cystathionine in each portion of the body were varied.
测定了日本蝮蛇各组织中含硫氨基酸、牛磺酸、胱硫醚、蛋氨酸和胱氨酸的浓度,以及胱硫醚β-合酶和γ-裂合酶的活性。在所检测组织中,牛磺酸的浓度高于其他含硫氨基酸的浓度。各组织中胱硫醚的浓度也远高于蛋氨酸和胱氨酸,但脑中胱硫醚的浓度低于蛋氨酸。在本研究检测的所有组织中,胱硫醚β-合酶的活性远高于胱硫醚γ-裂合酶。各组织中胱硫醚β-合酶与γ-裂合酶活性的比值为5.6至约85.6。还测定了身体分为八部分的肌肉和皮肤中含硫氨基酸的浓度。肌肉和皮肤各部分中蛋氨酸和胱氨酸的浓度几乎相同,但身体各部分中牛磺酸和胱硫醚的浓度有所不同。