Yaman A
Ankara University Faculty of Sciences, Department of Physics, 06100, Tandogan/Ankara, Turkey.
Physiol Chem Phys Med NMR. 2000;32(1):75-81.
The effects of J modulation on localized 1H NMR spectra were observed on metabolites with both a short T2 relaxation time like glutamate and a comparatively long T2 relaxation time like N-acetyl-L-aspartic acid (NAA). All examinations were performed by either the double spin-echo (PRESS) sequence or J-suppressed PRESS (JPRESS) sequence. Both of the sequences allow spectral editing and relaxation time studies of J coupled spins. Water-suppressed proton spectra were obtained at 1.5 T (GE Signa) from a 6-8 ml volume of interest. T1 and T2 relaxation times of some of the major brain metabolites were obtained by varying the repetition time and echo time of the JPRESS sequence.
在具有短T2弛豫时间的代谢物（如谷氨酸）和具有相对长T2弛豫时间的代谢物（如N-乙酰-L-天冬氨酸，NAA）上观察到了J调制对局部1H NMR谱的影响。所有检查均通过双自旋回波（PRESS）序列或J抑制PRESS（JPRESS）序列进行。这两种序列都允许对J耦合自旋进行光谱编辑和弛豫时间研究。在1.5 T（GE Signa）下从6-8 ml感兴趣体积中获得水抑制质子谱。通过改变JPRESS序列的重复时间和回波时间，获得了一些主要脑代谢物的T1和T2弛豫时间。
