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震颤的症状学

Semiology of Tremors.

作者信息

Molina-Negro P, Hardy J

出版信息

Can J Neurol Sci. 1975 Feb;2(1):23-9. doi: 10.1017/s0317167100019946.

DOI:10.1017/s0317167100019946
PMID:1097080
Abstract

Since the description by Galen in the 2nd Century, A.D., clinical neurology has acknowledged the existence of two types of tremor: that which occurs at rest and that occuring during the execution of movement. With the help of refined methods of analysis, E.M.G. and cinephotography, the authors have carried out a detailed clinical assessment in more than 400 patients. The basic criterion used to define a tremor was the classical definition of Dejerine: "An involuntary, rhythmical and symmetrical movement about an axis of equilibrium." As a result of this study, the conclusion has been reached that there are two types of tremor: postural tremor and tremor of attitude. Both are present while the limb remains immobile, whether by wilful design or when at rest in a position of posture and subject only to the action of gravity. During voluntary movement, tremor is not present. Irregular, asymmetrical and non-rhythmic oscillations may appear however - as in so-called intention tremor, of cerebellar origin - but this abnormal movement can hardly be called a real tremor. It is merely a manifestation of ataxia. As a consequence of this study, it is suggested that further understanding of the basic mechanism of tremor can be reached by the investigation of the central neural structures which are involved in the physiology of posture and attitude.

摘要

自公元2世纪盖伦进行描述以来,临床神经学就已认识到存在两种类型的震颤:静止时出现的震颤和运动执行过程中出现的震颤。借助精细的分析方法、肌电图和电影摄影技术,作者们对400多名患者进行了详细的临床评估。用于定义震颤的基本标准是德热里纳的经典定义:“围绕平衡轴的不自主、有节律且对称的运动。”这项研究的结果是得出结论,存在两种类型的震颤:姿势性震颤和姿势性震颤。无论肢体是有意保持不动,还是处于仅受重力作用的姿势休息时,这两种震颤都会出现。在自主运动期间,震颤不存在。然而,不规则、不对称且无节律的振荡可能会出现——如小脑起源的所谓意向性震颤——但这种异常运动很难被称为真正的震颤。它仅仅是共济失调的一种表现。这项研究的结果表明,通过研究参与姿势和体位生理学的中枢神经结构,可以进一步了解震颤的基本机制。

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