Kavouni A, Shibu M, Carver N
Department of Plastic and Reconstructive Surgery, Royal London Hospital, UK.
Clin Exp Dermatol. 2000 Jun;25(4):302-4. doi: 10.1046/j.1365-2230.2000.00648.x.
Squamous cell carcinoma arising in a skin graft is rare. Previous reports concern the use of skin in heterotopic locations namely the vagina and oral cavity. We report a case of squamous cell carcinoma, which arose in a skin graft used for resurfacing a scalp defect. The defect followed the excision of a basal cell carcinoma 11 years previously. The excision was incomplete and radiotherapy had been given. The possible pathological mechanisms for the development of a squamous cell carcinoma in transplanted skin are discussed.
皮肤移植中发生的鳞状细胞癌很罕见。以往的报道涉及在异位部位即阴道和口腔使用皮肤的情况。我们报告一例鳞状细胞癌，其发生于用于修复头皮缺损的皮肤移植处。该缺损是11年前切除基底细胞癌后遗留的。切除不完全且已进行放疗。文中讨论了移植皮肤中发生鳞状细胞癌的可能病理机制。
