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脑曲霉病,特别提及脑脊液检查结果

Cerebral aspergillosis with special reference to cerebrospinal fluid findings.

作者信息

Palo J, Haltia M, Uutela T

出版信息

Eur Neurol. 1975;13(3):224-31. doi: 10.1159/000114678.

DOI:10.1159/000114678
PMID:1097253
Abstract

A case of cerebral aspergillosis in a 69-year-old diabetic man is reported. The disease, initially presenting as headache and vertigo, was caused by Aspergillus fumigatus. Seven CSF specimens were examined. The main findings included decreased glucose and increased protein concentrations, leukocyte reaction and one positive culture for A. fumigatus. Neuropathological examination revealed granulomatous leptomeningitis and typical fungal hyphae. The process probably lasted for more than 1 year and was an important contributing factor to two brain stem infarcts.

摘要

报告了一例69岁糖尿病男性的脑曲霉病病例。该疾病最初表现为头痛和眩晕,由烟曲霉引起。对七份脑脊液样本进行了检查。主要发现包括葡萄糖降低、蛋白质浓度升高、白细胞反应以及一次烟曲霉培养阳性。神经病理学检查显示肉芽肿性软脑膜炎和典型的真菌菌丝。病程可能持续了一年多,是导致两次脑干梗死的重要因素。

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Cerebral aspergillosis with special reference to cerebrospinal fluid findings.脑曲霉病,特别提及脑脊液检查结果
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引用本文的文献

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Aspergillus meningitis: a rare clinical manifestation of central nervous system aspergillosis. Case report and review of 92 cases.曲霉性脑膜炎:中枢神经系统曲霉病的罕见临床表现。病例报告和 92 例病例回顾。
J Infect. 2013 Mar;66(3):218-38. doi: 10.1016/j.jinf.2012.11.003. Epub 2012 Nov 21.
2
Central nervous system Aspergillus fumigatus infection after near drowning.近乎溺亡后发生的中枢神经系统烟曲霉感染。
J Clin Pathol. 2004 Feb;57(2):202-4. doi: 10.1136/jcp.2003.010066.
3
Syndrome of the anterior spinal artery as the primary manifestation of aspergillosis.
以脊髓前动脉综合征为主要表现的曲霉病
Infection. 1995 Jul-Aug;23(4):240-2. doi: 10.1007/BF01781206.
4
Spinal arachnoiditis due to aspergillus meningitis in a previously healthy patient.
J Neurol. 1986 Feb;233(1):41-3. doi: 10.1007/BF00313990.
5
A guide to the recent literature on aspergillosis as caused by Aspergillus fumigatus, a fungus frequently found in self-heating organic matter.由烟曲霉引起的曲霉病近期文献指南,烟曲霉是一种常见于自热有机物质中的真菌。
Mycopathologia. 1979 Nov 30;69(1-2):67-81. doi: 10.1007/BF00428605.