近乎溺亡后发生的中枢神经系统烟曲霉感染。
Central nervous system Aspergillus fumigatus infection after near drowning.
作者信息
Kowacs P A, Monteiro de Almeida S, Pinheiro R L, Fameli H, Piovesan E J, Correia A, Werneck L C
机构信息
Neurology Division, Internal Medicine Department, Hospital de Clínicas da Universidade Federal do Paraná, 80060-900, Curitiba, Brazil.
出版信息
J Clin Pathol. 2004 Feb;57(2):202-4. doi: 10.1136/jcp.2003.010066.
Abstract
AIMS
To report the case of a 26 year old white man, who developed chronic meningitis and intracerebral granulomata 15 days after an episode of near drowning in a swamp.
METHODS
Aspergillus fumigatus was isolated from cerebrospinal fluid cultures.
RESULTS
The patient died 70 days after the symptoms were first noticed, and seven days after a subarachnoid haemorrhage. Aspergillus has never been reported before as a cause of intracranial infection after near drowning.
CONCLUSIONS
Physicians must be aware of this possibility when confronted with such a situation, because there are now effective therapeutic options for systemic aspergillosis.
摘要
目的
报告一名26岁白人男性的病例，该患者在沼泽地发生近乎溺水事件15天后出现慢性脑膜炎和脑内肉芽肿。
方法
从脑脊液培养物中分离出烟曲霉。
结果
患者在首次出现症状70天后死亡，蛛网膜下腔出血7天后死亡。此前从未有过烟曲霉作为近乎溺水后颅内感染病因的报道。
结论
面对这种情况时，医生必须意识到这种可能性，因为目前对于系统性曲霉病有有效的治疗选择。
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