Vogt T, Jones P
Dept of Plant Secondary Metabolism, Leibniz Institute for Plant Biochemistry, 06120 Halle/Saale, Weinberg 3, Germany.
Trends Plant Sci. 2000 Sep;5(9):380-6. doi: 10.1016/s1360-1385(00)01720-9.
Glycosyltransferases of plant secondary metabolism transfer nucleotide-diphosphate-activated sugars to low molecular weight substrates. Until recently, glycosyltransferases were thought to have only limited influence on the basic physiology of the plant. This view has changed. Glycosyltransferases might in fact have an important role in plant defense and stress tolerance. Recent results obtained with several recombinant enzymes indicate that many glycosyltransferases are regioselective or regiospecific rather than highly substrate specific. This might indicate how plants evolve novel secondary products, placing enzymes with broad substrate specificities downstream of the conserved, early, pivotal enzymes of plant secondary metabolism.
植物次生代谢中的糖基转移酶将二磷酸核苷酸激活的糖类转移到低分子量底物上。直到最近，人们还认为糖基转移酶对植物的基本生理功能影响有限。但这种观点已经改变。事实上，糖基转移酶可能在植物防御和胁迫耐受性方面发挥重要作用。最近对几种重组酶的研究结果表明，许多糖基转移酶具有区域选择性或区域特异性，而非高度底物特异性。这可能揭示了植物如何进化出新的次生产物，将具有广泛底物特异性的酶置于植物次生代谢中保守、早期、关键酶的下游。
