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五种长支架的力学性能比较。

Mechanical Properties of Five Long Stents Compared.

作者信息

Ormiston JA, Ruygrok PN, Webster MW, Stewart JT, White HD

机构信息

Mercy Hospital, 98 Mountain Road Epsom, Auckland 3, New Zealand.

出版信息

J Invasive Cardiol. 1998 Apr;10 Suppl B:35B.

Abstract

BACKGROUND

At Green Lane Hospital, 36% of interventional patients received one or more long stents. Long stents are cost-effective, increase procedural speed and increase the range of patients that can be treated percutaneously. With the increasing array of long stent designs available, the interventionalist needs objective comparative data for rational stent selection. AIM: To compare the mechanical and physical characteristics of five long stent designs. METHODS AND MATERIALS: Characteristics investigated were radiographic appearance, stent stiffness, radial strength, force to dislodge the stent from its balloon and simulated side branch dilatation. Long stents studied were the AVEGFX 30 mm, beStent 25 mm, Crown 30 mm, Multi-Link 35 mm and NIR 32 mm. Radiographic appearance was assessed on plain non-cine film without magnification. Stiffness was tested in the unexpanded and in the expanded states using an instron to measure the force required to bend the stent 1.5 mm within its elastic range. Radial strength of the stents expanded within a tecoflex tube was assessed by subjecting each stent to pressure increments within a pressure chamber and measuring diameter reduction. The force to dislodge a stent from its balloon was measured with an instron attached to the stent with adhesive tape. Dilatation through the side of each stent (expanded to 3.5 mm) was carried out in a plexiglass phantom with 2.5, 3.0, 3.5 and 4.0 balloons. The side lumen created and the distal stenosis produced were measured. RESULTS: Radiographic appearance and radiodensity vary between stents. All stents become stiffer upon expansion. Stent flexibility varies markedly between stent designs. Flexibility and radial strength are independent characteristics. Hand crimped stents tested were less resistant to dislodgement than the manufacturer mounted stents. Side branch dilatation produced varying downstream stenosis in stents studied. Side lumen size varied with stent design, and in some cases ballon size. CONCLUSION: Objective data assist the interventionalist in choosing rationally between stents. These data assist in tailoring stent selection for particular lesions.

摘要

背景

在格林莱恩医院,36%的介入治疗患者接受了一个或多个长支架。长支架具有成本效益,可提高手术速度,并扩大经皮治疗患者的范围。随着可用长支架设计种类的不断增加,介入专家需要客观的比较数据来合理选择支架。目的:比较五种长支架设计的机械和物理特性。方法和材料:所研究的特性包括影像学表现、支架硬度、径向强度、将支架从球囊上取下所需的力以及模拟侧支扩张。研究的长支架有AVEGFX 30毫米、beStent 25毫米、Crown 30毫米、Multi-Link 35毫米和NIR 32毫米。在无放大的普通非电影胶片上评估影像学表现。使用英斯特朗在未扩张和扩张状态下测试硬度,以测量在弹性范围内将支架弯曲1.5毫米所需的力。通过在压力室内对每个支架施加压力增量并测量直径减小来评估在tecoflex管内扩张的支架的径向强度。用胶带将英斯特朗连接到支架上,测量将支架从球囊上取下所需的力。在带有2.5、3.0、3.5和4.0球囊的有机玻璃模型中对每个支架(扩张至3.5毫米)的侧面进行扩张。测量形成的侧腔和产生的远端狭窄。结果:不同支架的影像学表现和放射密度各不相同。所有支架在扩张后都会变硬。不同支架设计之间的支架柔韧性差异明显。柔韧性和径向强度是相互独立的特性。测试的手工卷曲支架比制造商安装的支架更不易脱落。在所研究的支架中,侧支扩张产生了不同程度的下游狭窄。侧腔大小因支架设计而异,在某些情况下还因球囊大小而异。结论:客观数据有助于介入专家在支架之间进行合理选择。这些数据有助于针对特定病变量身定制支架选择。

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