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氨苄西林与阿贝卡星联合用药对携带aph(2")-Id基因的耐万古霉素和高水平庆大霉素屎肠球菌的体外协同活性。

In-vitro synergistic activity of the combination of ampicillin and arbekacin against vancomycin-and high-level gentamicin-resistant Enterococcus faecium with the aph(2")-Id gene.

作者信息

Kak V, You I, Zervos M J, Kariyama R, Kumon H, Chow J W

机构信息

Research and Medical Service, John D Dingell VA Medical Center, and Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI 48201, USA.

出版信息

Diagn Microbiol Infect Dis. 2000 Aug;37(4):297-9. doi: 10.1016/s0732-8893(00)00155-3.

DOI:10.1016/s0732-8893(00)00155-3
PMID:10974585
Abstract

The combination of ampicillin plus arbekacin produced synergistic killing against 8 of 13 vancomycin-, ampicillin-, gentamicin-, and streptomycin-resistant Enterococcus faecium isolates that possess the high-level gentamicin resistance gene, aph(2")-Id. This combination may prove useful in treating infections caused by multiresistant enterococci.

摘要

氨苄西林与阿贝卡星联合用药对13株耐万古霉素、氨苄西林、庆大霉素和链霉素的粪肠球菌具有协同杀菌作用，这些菌株携带高水平庆大霉素耐药基因aph(2")-Id。这种联合用药可能对治疗多重耐药肠球菌引起的感染有用。

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In-vitro synergistic activity of the combination of ampicillin and arbekacin against vancomycin-and high-level gentamicin-resistant Enterococcus faecium with the aph(2")-Id gene.氨苄西林与阿贝卡星联合用药对携带aph(2")-Id基因的耐万古霉素和高水平庆大霉素屎肠球菌的体外协同活性。
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